Anti Inflammatory Pain Relieving Drugs Phenacetin Raw Powder CAS
Molecular formula: C10H13NO2
Molecular weight: 179.2158
Category: raw material medicine, antipyretic and analgesic drugs
Characteristics: This product is white, there is a flash of scale
like crystal or white crystalline powder, no
smell, taste bitter. This product is dissolved in ethanol or
chloroform, slightly soluble in boiling water
Soluble in water.
Phenacetis is a pain-relieving and fever-reducing drug.
Phenacetin was widely used until the third quarter of the twentieth
century, often in the form of an
"A.P.C." or aspirin-phenacetin-caffeine compound analgesic, as a
remedy for fever and pain. An early formulation (1919) was
Vincent's APC in Australia. However the U.S. Food and Drug
Administration ordered the withdrawal of drugs containing
phenacetin in November 1983, owing to its carcinogenic and
kidney-damaging properties (Federal Register of October 5, 1983 (48
FR 45466)). It was also banned
in India. As a result, some branded, previously phenacetin-based
preparations continued to be sold,
but with the phenacetin replaced by safer alternatives. A popular
brand of phenacetin was Roche's Saridon, which was reformulated in
1983 to contain propyphenazone, paracetamol and caffeine.
Coricidin was also reformulated without phenacetin. Paracetamol is
a metabolite of phenacetin with
similar analgesic and antipyretic effects, but the new formulation
has not been found to have
Phenacetin is now being used as a cutting agent to adulterate
cocaine in the UK and Canada,
owing to the similar physical features of the two drugs.
Due to low cost phenacetin is used for research into the physical
and refractive properties of crystals.
It is an ideal compound for this type of research.
Certificate Of Analysis:
|Specific Rotation||+39°~ +43°||+40.2°|
|Organic Volatile Impurities||Conform||Conform|
|Loss On Drying||≤0.50%||0.27%|
|Residue On Ignition||≤0.10%||0.015%|
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